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2024 Publications

  • Zhang J, Zhang F, Porter KI, Dakup PP, Wang S, Robertson GP, Gaddameedhi S, Zhu J. Telomere dysfunction in Tert knockout mice delays BrafV600E -induced melanoma development. Int J Cancer. 2024 Feb 1;154(3):548-560. doi: 10.1002/ijc.34713. Epub 2023 Sep 20. PMID: 37727982.

2023 Publications

  • Koritala BSC, Dakup PP, Porter KI, Gaddameedhi S. The impact of shift-work light conditions on tissue-specific circadian rhythms of canonical clock genes: insights from a mouse model study. F1000Res. 2023 Aug 17;12:762. doi: 10.12688/f1000research.136998.2. PMID: 37576540; PMCID: PMC10422053.
  • Mishra SK, Gaddameedhi S. A new role of TRPM8 in circadian rhythm and molecular clock. Acta Physiol (Oxf). 2023 Mar;237(3):e13934. doi: 10.1111/apha.13934. Epub 2023 Jan 20. PMID: 36636860.

2022 Publications

  • Kelly MR, Yuen F, Satterfield BC, Auchus RJ, Gaddameedhi S, Van Dongen HPA, Liu PY. Endogenous Diurnal Patterns of Adrenal and Gonadal Hormones During a 24-Hour Constant Routine After Simulated Shift Work. J Endocr Soc. 2022 Sep 29;6(12):bvac153. doi: 10.1210/jendso/bvac153. Erratum in: J Endocr Soc. 2023 Nov 16;7(12):bvad138. PMID: 36330292; PMCID: PMC9620969.
  • Kyle JE, Bramer LM, Claborne D, Stratton KG, Bloodsworth KJ, Teeguarden JG, Gaddameedhi S, Metz TO, Van Dongen HPA. Simulated Night-Shift Schedule Disrupts the Plasma Lipidome and Reveals Early Markers of Cardiovascular Disease Risk. Nat Sci Sleep. 2022 May 21;14:981-994. doi: 10.2147/NSS.S363437. Erratum in: Nat Sci Sleep. 2023 Jun 26;15:477-478. PMID: 35645584; PMCID: PMC9133431.
  • Dakup PP, Greer AJ, Gaddameedhi S. Let’s talk about sex: A biological variable in immune response against melanoma. Pigment Cell Melanoma Res. 2022 Mar;35(2):268-279. doi: 10.1111/pcmr.13028. Epub 2022 Feb 3. PMID: 35076986; PMCID: PMC9305920.
  • Muck RA, Hudson AN, Honn KA, Gaddameedhi S, Van Dongen HPA. Working around the Clock: Is a Person’s Endogenous Circadian Timing for Optimal Neurobehavioral Functioning Inherently Task-Dependent? Clocks Sleep. 2022 Feb 11;4(1):23-36. doi: 10.3390/clockssleep4010005. PMID: 35225951; PMCID: PMC8883919.
  • Koritala BSC, Porter KI, Sarkar S, Gaddameedhi S. Circadian disruption and cisplatin chronotherapy for mammary carcinoma. Toxicol Appl Pharmacol. 2022 Feb 1;436:115863. doi: 10.1016/j.taap.2022.115863. Epub 2022 Jan 5. PMID: 34998857; PMCID: PMC8792356.
  • Goodenow D, Greer AJ, Cone SJ, Gaddameedhi S. Circadian effects on UV-induced damage and mutations. Mutat Res Rev Mutat Res. 2022 Jan-Jun;789:108413. doi: 10.1016/j.mrrev.2022.108413. Epub 2022 Feb 17. PMID: 35690416; PMCID: PMC9188652.

2021 Publications

  • Sarkar S, Porter KI, Dakup PP, Gajula RP, Koritala BSC, Hylton R, Kemp MG, Wakamatsu K, Gaddameedhi S. Circadian clock protein BMAL1 regulates melanogenesis through MITF in melanoma cells. Pigment Cell Melanoma Res. 2021 Sep;34(5):955-965. doi: 10.1111/pcmr.12998. Epub 2021 Jul 6. PMID: 34160901; PMCID: PMC8429232.
  • Xu T, Cheng D, Zhao Y, Zhang J, Zhu X, Zhang F, Chen G, Wang Y, Yan X, Robertson GP, Gaddameedhi S, Lazarus P, Wang S, Zhu J. Polymorphic tandem DNA repeats activate the human telomerase reverse transcriptase gene. Proc Natl Acad Sci U S A. 2021 Jun 29;118(26):e2019043118. doi: 10.1073/pnas.2019043118. PMID: 34155099; PMCID: PMC8256013.
  • Liu PY, Irwin MR, Krueger JM, Gaddameedhi S, Van Dongen HPA. Night shift schedule alters endogenous regulation of circulating cytokines. Neurobiol Sleep Circadian Rhythms. 2021 Mar 5;10:100063. doi: 10.1016/j.nbscr.2021.100063. PMID: 33748539; PMCID: PMC7970107.
  • Hayter EA, Wehrens SMT, Van Dongen HPA, Stangherlin A, Gaddameedhi S, Crooks E, Barron NJ, Venetucci LA, O’Neill JS, Brown TM, Skene DJ, Trafford AW, Bechtold DA. Distinct circadian mechanisms govern cardiac rhythms and susceptibility to arrhythmia. Nat Commun. 2021 Apr 30;12(1):2472. doi: 10.1038/s41467-021-22788-8. Erratum in: Nat Commun. 2021 Dec 8;12(1):7284. PMID: 33931651; PMCID: PMC8087694.
  • Koritala BSC, Porter KI, Arshad OA, Gajula RP, Mitchell HD, Arman T, Manjanatha MG, Teeguarden J, Van Dongen HPA, McDermott JE, Gaddameedhi S. Night shift schedule causes circadian dysregulation of DNA repair genes and elevated DNA damage in humans. J Pineal Res. 2021 Apr;70(3):e12726. doi: 10.1111/jpi.12726. Epub 2021 Mar 14. PMID: 33638890; PMCID: PMC8011353.

2020 Publications

  • Dakup PP, Porter KI, Little AA, Zhang H, Gaddameedhi S. Sex differences in the association between tumor growth and T cell response in a melanoma mouse model. Cancer Immunol Immunother. 2020 Oct;69(10):2157-2162. doi: 10.1007/s00262-020-02643-3. Epub 2020 Jun 25. PMID: 32638080; PMCID: PMC7529921.
  • Khalyfa A, Gaddameedhi S, Crooks E, Zhang C, Li Y, Qiao Z, Trzepizur W, Kay SA, Andrade J, Satterfield BC, Hansen DA, Kheirandish-Gozal L, Van Dongen HPA, Gozal D. Circulating Exosomal miRNAs Signal Circadian Misalignment to Peripheral Metabolic Tissues. Int J Mol Sci. 2020 Sep 3;21(17):6396. doi: 10.3390/ijms21176396. PMID: 32899117; PMCID: PMC7503323.
  • Sarkar S, Gaddameedhi S. Solar ultraviolet-induced DNA damage response: Melanocytes story in transformation to environmental melanomagenesis. Environ Mol Mutagen. 2020 Aug;61(7):736-751. doi: 10.1002/em.22370. Epub 2020 May 8. PMID: 32281145; PMCID: PMC9675355.
  • Dakup PP, Porter KI, Gaddameedhi S. The circadian clock protects against acute radiation-induced dermatitis. Toxicol Appl Pharmacol. 2020 Jul 15;399:115040. doi: 10.1016/j.taap.2020.115040. Epub 2020 May 15. PMID: 32422325; PMCID: PMC10523357.
  • Dakup PP, Porter KI, Gajula RP, Goel PN, Cheng Z, Gaddameedhi S. The circadian clock protects against ionizing radiation-induced cardiotoxicity. FASEB J. 2020 Feb;34(2):3347-3358. doi: 10.1096/fj.201901850RR. Epub 2020 Jan 10. PMID: 31919902; PMCID: PMC9677419.

2019 Publications

  • Ashok Kumar PV, Dakup PP, Sarkar S, Modasia JB, Motzner MS, Gaddameedhi S. It’s About Time: Advances in Understanding the Circadian Regulation of DNA Damage and Repair in Carcinogenesis and Cancer Treatment Outcomes. Yale J Biol Med. 2019 Jun 27;92(2):305-316. PMID: 31249491; PMCID: PMC6585512.
  • Skornyakov E, Gaddameedhi S, Paech GM, Sparrow AR, Satterfield BC, Shattuck NL, Layton ME, Karatsoreos I, VAN Dongen HPA. Cardiac autonomic activity during simulated shift work. Ind Health. 2019 Feb 5;57(1):118-132. doi: 10.2486/indhealth.2018-0044. Epub 2018 Aug 8. PMID: 30089765; PMCID: PMC6363578.

2018 Publications

  • Skene DJ, Skornyakov E, Chowdhury NR, Gajula RP, Middleton B, Satterfield BC, Porter KI, Van Dongen HPA, Gaddameedhi S. Separation of circadian- and behavior-driven metabolite rhythms in humans provides a window on peripheral oscillators and metabolism. Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):7825-7830. doi: 10.1073/pnas.1801183115. Epub 2018 Jul 10. Erratum in: Proc Natl Acad Sci U S A. 2021 Sep 7;118(36): PMID: 29991600; PMCID: PMC6065025.
  • Dakup PP, Porter KI, Little AA, Gajula RP, Zhang H, Skornyakov E, Kemp MG, Van Dongen HPA, Gaddameedhi S. The circadian clock regulates cisplatin-induced toxicity and tumor regression in melanoma mouse and human models. Oncotarget. 2018 Feb 20;9(18):14524-14538. doi: 10.18632/oncotarget.24539. PMID: 29581861; PMCID: PMC5865687.
  • Sarkar S, Gaddameedhi S. UV-B-Induced Erythema in Human Skin: The Circadian Clock Is Ticking. J Invest Dermatol. 2018 Feb;138(2):248-251. doi: 10.1016/j.jid.2017.09.002. PMID: 29389325.